caption a7 reference strain azithromycin mic  (ATCC)

Journal: Journal of Clinical Microbiology

Article Title: Testing of In Vitro Susceptibility of Neisseria gonorrhoeae to Azithromycin: Comparison of Disk Diffusion and Reference Agar Dilution Methods

doi: 10.1128/JCM.01398-20

Figure Lengend Snippet: Scattergram of MICs versus zone diameters (n = 189) for 15-μg azithromycin disks from BBL and Oxoid. The horizontal solid line represents the CLSI breakpoint for azithromycin. The vertical dashed line indicates the zone diameter breakpoint proposed in this study. Very major and major discrepancies are highlighted in light gray and dark gray, respectively.

Article Snippet: Moreover, based on disk diffusion data for nine replicates per isolate and combining the BBL and Oxoid results obtained, tentative quality control ranges for the nine N. gonorrhoeae WHO reference strains were determined. table ft1 table-wrap mode="anchored" t5 TABLE 1 caption a7 Reference strain Azithromycin MIC (μg/ml) Zone diam (mm) Reference MIC a MIC in present study Range Median WHO F 0.125 0.125–0.25 32–37 34 WHO N 0.25 0.125–0.25 36–38 37 WHO O 0.25 0.25–0.5 32–37 34 WHO P 4 4 22–25 24 WHO U 4 4 22–25 23 WHO W 0.5 0.25–0.5 35–38 36 WHO X 0.5 0.25–0.5 36–38 38 WHO Y 1 0.5–1 32–37 36 WHO Z 1 1 30–33 31 ATCC 49226 0.25–1 0.25–0.5 35–37 36 Open in a separate window a Based on references 13 and 7 .

Techniques:

Journal: Journal of Clinical Microbiology

Article Title: Testing of In Vitro Susceptibility of Neisseria gonorrhoeae to Azithromycin: Comparison of Disk Diffusion and Reference Agar Dilution Methods

doi: 10.1128/JCM.01398-20

Figure Lengend Snippet: Azithromycin MIC and inhibition zone diameter results of N. gonorrhoeae ATCC 49226 and nine WHO reference strains

Article Snippet: Moreover, based on disk diffusion data for nine replicates per isolate and combining the BBL and Oxoid results obtained, tentative quality control ranges for the nine N. gonorrhoeae WHO reference strains were determined. table ft1 table-wrap mode="anchored" t5 TABLE 1 caption a7 Reference strain Azithromycin MIC (μg/ml) Zone diam (mm) Reference MIC a MIC in present study Range Median WHO F 0.125 0.125–0.25 32–37 34 WHO N 0.25 0.125–0.25 36–38 37 WHO O 0.25 0.25–0.5 32–37 34 WHO P 4 4 22–25 24 WHO U 4 4 22–25 23 WHO W 0.5 0.25–0.5 35–38 36 WHO X 0.5 0.25–0.5 36–38 38 WHO Y 1 0.5–1 32–37 36 WHO Z 1 1 30–33 31 ATCC 49226 0.25–1 0.25–0.5 35–37 36 Open in a separate window a Based on references 13 and 7 .

Techniques: Inhibition

Journal: Journal of Clinical Microbiology

Article Title: Testing of In Vitro Susceptibility of Neisseria gonorrhoeae to Azithromycin: Comparison of Disk Diffusion and Reference Agar Dilution Methods

doi: 10.1128/JCM.01398-20

Figure Lengend Snippet: Retrospective analysis of azithromycin MICs versus inhibition zone diameters for 2,344 N. gonorrhoeae isolates cultured across Argentina from 2016 to June 2019. The horizontal red solid line represents the CLSI breakpoint for azithromycin. The vertical red solid line indicates the zone diameter breakpoint proposed in this study.

Article Snippet: Moreover, based on disk diffusion data for nine replicates per isolate and combining the BBL and Oxoid results obtained, tentative quality control ranges for the nine N. gonorrhoeae WHO reference strains were determined. table ft1 table-wrap mode="anchored" t5 TABLE 1 caption a7 Reference strain Azithromycin MIC (μg/ml) Zone diam (mm) Reference MIC a MIC in present study Range Median WHO F 0.125 0.125–0.25 32–37 34 WHO N 0.25 0.125–0.25 36–38 37 WHO O 0.25 0.25–0.5 32–37 34 WHO P 4 4 22–25 24 WHO U 4 4 22–25 23 WHO W 0.5 0.25–0.5 35–38 36 WHO X 0.5 0.25–0.5 36–38 38 WHO Y 1 0.5–1 32–37 36 WHO Z 1 1 30–33 31 ATCC 49226 0.25–1 0.25–0.5 35–37 36 Open in a separate window a Based on references 13 and 7 .

Techniques: Inhibition, Cell Culture

Journal: Journal of Clinical Microbiology

Article Title: Testing of In Vitro Susceptibility of Neisseria gonorrhoeae to Azithromycin: Comparison of Disk Diffusion and Reference Agar Dilution Methods

doi: 10.1128/JCM.01398-20

Figure Lengend Snippet: Azithromycin MIC values and disk diffusion zone diameters (using BBL and Oxoid disks) recorded by two laboratories (A and B) when testing ten N. gonorrhoeae strains in duplicate on two different days. The horizontal solid line represents the CLSI breakpoint for azithromycin. The vertical dashed line indicates the zone diameter breakpoint proposed in this study.

Article Snippet: Moreover, based on disk diffusion data for nine replicates per isolate and combining the BBL and Oxoid results obtained, tentative quality control ranges for the nine N. gonorrhoeae WHO reference strains were determined. table ft1 table-wrap mode="anchored" t5 TABLE 1 caption a7 Reference strain Azithromycin MIC (μg/ml) Zone diam (mm) Reference MIC a MIC in present study Range Median WHO F 0.125 0.125–0.25 32–37 34 WHO N 0.25 0.125–0.25 36–38 37 WHO O 0.25 0.25–0.5 32–37 34 WHO P 4 4 22–25 24 WHO U 4 4 22–25 23 WHO W 0.5 0.25–0.5 35–38 36 WHO X 0.5 0.25–0.5 36–38 38 WHO Y 1 0.5–1 32–37 36 WHO Z 1 1 30–33 31 ATCC 49226 0.25–1 0.25–0.5 35–37 36 Open in a separate window a Based on references 13 and 7 .

Techniques: Diffusion-based Assay